Homo sp. nov. 'Denisovans'
Denisovans
Taxonomy & Nomenclature
Synonym/s: Homo sp. Altai (source); Homo sapiens ssp. Denisova (source); Homo denisovan; Homo sapiens denisovan; Homo altai; Homo altaensis (used by Agadjanian & Shunkov, 2018); Homo denisensis (used by Agadjanian & Shunkov, 2018)
Conservation Status
Extinct
Last record: c. 39,000 BC?
Distribution
Russia
Biology
Hypodigm
Media
References
Adel, Susan, Kakularam, Kumar Reddy, Horn, Thomas, Reddanna, Pallu, Kuhn, Hartmut and Heydeck, Dagmar. (2015). Leukotriene signaling in the extinct human subspecies Homo denisovan and Homo neanderthalensis. Structural and functional comparison with Homo sapiens. Archives of Biochemistry and Biophysics 565: 17-24.
Agadjanian, A. K. and Shunkov, M. V. (2018). Paleolithic Man of Denisova Cave and Zoogeography of Pleistocene Mammals of Northwestern Altai. Paleontological Journal 52(1): 66-89. [Abstract]
Amos, William. (2021). Correlated and geographically predictable Neanderthal and Denisovan legacies are difficult to reconcile with a simple model based on inter-breeding. R. Soc. Open Sci. 8: 201229. https://doi.org/10.1098/rsos.201229
Bower, Bruce. (2012). Denisovan DNA reveals history of enigmatic group: Extinct Neandertal relative lived about 75,000 years ago. ScienceNews 182(6): 5-6. [Abstract]
Brown, S. et al. Identification of a new hominin bone from Denisova Cave, Siberia using collagen fingerprinting and mitochondrial DNA analysis. Sci. Rep. 6, 23559 (2016).
Browning, Sharon R. et al. (In Press, 2018). Analysis of Human Sequence Data Reveals Two Pulses of Archaic Denisovan Admixture. Cell. https://doi.org/10.1016/j.cell.2018.02.031
Fahu Chen, Frido Welker, Chuan-Chou Shen, Shara E. Bailey, Inga Bergmann, Simon Davis, Huan Xia, Hui Wang, Roman Fischer, Sarah E. Freidline, Tsai-Luen Yu, Matthew M. Skinner, Stefanie Stelzer, Guangrong Dong, Qiaomei Fu, Guanghui Dong, Jian Wang, Dongju Zhang & Jean-Jacques Hublin. A late Middle Pleistocene Denisovan mandible from the Tibetan Plateau. Nature, 2019 DOI: 10.1038/s41586-019-1139-x [Abstract]
Chen, F., Xia, H., Jia, Z. et al. (2022). Earliest hand- and footprint art indicates that Denisovans may have occupied the interior of the high-altitude Tibetan Plateau since 200 thousand years ago. Sci. China Earth Sci. 65: 769-772. https://doi.org/10.1007/s11430-021-9899-y
Cooper, A. and Stringer, Chris B. (2013). Did the Denisovans cross the Wallace line? Science 342(6156): 321-323. [Abstract]
Dannemann, M., Andrés, A. M. and Kelso, J. (2016). Introgression of Neandertal- and Denisovan-like Haplotypes Contributes to Adaptive Variation in Human Toll-like Receptors. American Journal of Human Genetics 98(1): 22-33.
Demeter, Fabrice et al. (2022). A Middle Pleistocene Denisovan molar from the Annamite Chain of northern Laos. Nature Communications 13: 2557. https://doi.org/10.1038/s41467-022-29923-z
Di Vincenzo, Fabio and Manzi, Giorgio. (2023). Homo heidelbergensis as the Middle Pleistocene common ancestor of Denisovans, Neanderthals and modern humans. Journal of Mediterranean Earth Sciences. doi:10.13133/2280-6148/18074
Gibbons, Ann. (2012). Ancient DNA. A crystal-clear view of an extinct girl’s genome. Science 337(6098): 1028-1029.
Gibbons, Ann. (2017). Ancient skulls may belong to elusive humans called Denisovans. Science 355(6328): 899.
Gibbons, Ann. (2019a). Moderns said to mate with late-surviving Denisovans. Science 364(6435): 12-13. [Summary]
Gibbons, Ann. (2019b). Ancient jaw gives elusive Denisovans a face. Science 364(6439): 418-419. [Summary]
Gibbons, Ann. (2020). Denisovan DNA found in cave on Tibetan Plateau. Science 370(6516): 512-513. DOI: 10.1126/science.370.6516.512 [Summary]
Gokhman, David et al. (2014). Reconstructing the DNA Methylation Maps of the Neandertal and the Denisovan. Science 344(6183): 523-527. [Abstract]
Greer, Cory et al. (2021). Deleterious variants in genes regulating mammalian reproduction in Neanderthals, Denisovans and extant humans. Human Reproduction 36(3): 734-755. [Abstract]
Gunbin, Konstantin V. et al. (2015). The evolution of Homo sapiens denisova and Homo sapiens neanderthalensis miRNA targeting genes in the prenatal and postnatal brain. BMC Genomics 2015 16(Suppl 13): S4.
Gupta, Deepak, Ambalavanan, Sivanoli and Bangaru, Pandu Ranga Rao. (2016). Connecting The Dots in Theoretical Anthropology: Was This One of The Earliest Contemplation About Homo sapiens sapiens' Fight for Survival and Interactions with Homo sapiens neanderthalensis and Homo sapiens denisova? WebmedCentral PRIMATOLOGY 7(9): WMC005184.
Hallak, Keren Levinstein and Rosset, Saharon. (2023). Dating Ancient Splits in Phylogenetic Trees, with Application to the Human-Neanderthal Split. Research Square preprint. https://doi.org/10.21203/rs.3.rs-2991806/v1
Hawks, J. (2013). Significance of Neandertal and Denisovan genomes in human evolution. Annual Review of Anthropology 42: 433-449.
Jacobs, Zenobia et al. (2019). Timing of archaic hominin occupation of Denisova Cave in southern Siberia. Nature 565: 594-599. [Abstract]
Koller, Dora et al. (2022). Denisovan and Neanderthal archaic introgression differentially impacted the genetics of complex traits in modern populations. BMC Biology 20: 249. https://doi.org/10.1186/s12915-022-01449-2
Krause, Johannes; Fu, Qiaomei; Good, Jeffrey M.; Viola, Bence; Shunkov, Michael V.; Derevianko, Anatoli P. & Pääbo, Svante. (2010). The complete mitochondrial DNA genome of an unknown hominin from southern Siberia. Nature 464(7290): 894-897. [Abstract]
Kuzmin, Yaroslav V. et al. (2021). Denisovans, Neanderthals, and Early Modern Humans: A Review of the Pleistocene Hominin Fossils from the Altai Mountains (Southern Siberia). Journal of Archaeological Research. https://doi.org/10.1007/s10814-021-09164-2 [Abstract]
Li, Zhan-Yang et al. (2017). Late Pleistocene archaic human crania from Xuchang, China. Science 355(6328): 969-972. [Abstract]
Lowery RK, Uribe G, Jimenez EB, Weiss MA, Herrera KJ, Regueiro M, Herrera RJ (2013) Neanderthal and Denisova genetic affinities with contemporary humans: introgression versus common ancestral polymorphisms. Gene 530: 83-94.
Meyer, M., Kircher, M., Gansauge, M. T., Li, H. et al. (2012) A high-coverage genome sequence from an archaic Denisovan individual. Science 338(6104): 222-226.
Neubauer, Fernanda. (2014). A Brief Overview of the Last 10 Years of Major Late Pleistocene Discoveries in the Old World: Homo floresiensis, Neanderthal, and Denisovan. Journal of Anthropology 2014(581689): 1-7.
Oikkonen, Venla. (2019). Entanglements of Time, Temperature, Technology, and Place in Ancient DNA Research: The Case of the Denisovan Hominin. Science, Technology, & Human Values. DOI: 10.1177/0162243919879991
Pennisi, E. (2013). More genomes from Denisova Cave show mixing of early human groups. Science 340(6134): 799. [Abstract]
Petr, Martin et al. (2020). The evolutionary history of Neandertal and Denisovan Y chromosomes. bioRxiv preprint. doi: https://doi.org/10.1101/2020.03.09.983445
Peyrégne, Stéphane, Slon, Viviane and Kelso, Janet. (2023). More than a decade of genetic research on the Denisovans. Nature Reviews Genetics. https://doi.org/10.1038/s41576-023-00643-4
Price, Michael. (2019). Face of the mysterious Denisovans emerges. Science 365(6459): 1232. [Abstract]
Reich D, Green RE, Kircher M, Krause J, Patterson N, Durand EY, Viola B, Briggs AW, Stenzel U, Johnson PLF, Maricic T, Good JM, Marques-Bonet T, Alkan C, Fu Q, Mallick S, Li H, Meyer M, Eichler EE, Stoneking M, Richards M, Talamo S, Shunkov MV, Derevianko AP, Hublin J-J, Kelso J, Slatkin M, Pääbo S. (2010). Genetic history of an archaic hominin group from Denisova Cave in Siberia. Nature 468: 1053-1060.
Reich D, Patterson N, Kircher M, Delfin F, Nandineni MR, Pugach I, Ko AM, Ko YC, Jinam TA, Phipps ME, Saitou N, Wollstein A, Kayser M, Pääbo S, Stoneking M. (2011). Denisova admixture and the first modern human dispersals into Southeast Asia and Oceania. Am. J .Hum. Genet. 89: 516-528.
Rogers, Alan R. et al. (2019). Neanderthal-Denisovan ancestors interbred with a distantly-related hominin. bioRxiv preprint. doi: http://dx.doi.org/10.1101/657247
Ruan, Jiaoyang et al. (2023). Climate shifts orchestrated hominin interbreeding events across Eurasia. Science 381(6658): add4459. https://doi.org/10.1126/science.add4459
Sankararaman S., Mallick S., Patterson N. et al. (2016). The Combined Landscape of Denisovan and Neanderthal Ancestry in Present-Day Humans. Current Biology 26(9): 1241-1247.
Sawyer, Susanna et al. (2015). Nuclear and mitochondrial DNA sequences from two Denisovan individuals. Proc. Natl. Acad. Sci. USA 112(51): 15696-15700. [Abstract]
Schaefer, Nathan K. et al. (2021). An ancestral recombination graph of human, Neanderthal, and Denisovan genomes. Sci. Adv. 7: eabc0776.
Skoglund, P., and M. Jakobsson. (2011). Archaic human ancestry in East Asia. Proc. Natl. Acad. Sci. USA 108: 18301-18306.
Slon, Viviane et al. (2017a). A fourth Denisovan individual. Sci. Adv. 3, e1700186.
Slon, Viviane et al. (2017b). Neandertal and Denisovan DNA from Pleistocene sediments. Science. DOI: 10.1126/science.aam9695
Slon, Viviane et al. (2018). The genome of the offspring of a Neanderthal mother and a Denisovan father. Nature 561: 113-116. [Abstract]
Srinivasan, Amrutha. (2020). A reevaluation of the phylogenetic tree for the genus Homo: a reclassification based on contemporary evidence. Honours thesis, University of Texas.
Stewart J.R., Stringer C.B. 2012 Human evolution out of Africa: The role of refugia and climate change. Science 335(6074), 1317-1321.
Stringer, Chris and Barnes, Ian. (2015). Deciphering the Denisovans. PNAS. doi: 10.1073/pnas.1522477112 [Abstract]
Taylor, John S. (2014). Did Neanderthals and Denisovans have Our De Novo Genes? Journal of Molecular Evolution 78(6): 321-323.
Teixeira, João C. et al. (2021). Widespread Denisovan ancestry in Island Southeast Asia but no evidence of substantial super-archaic hominin admixture. Nature Ecology & Evolution 5: 616-624. https://doi.org/10.1038/s41559-021-01408-0
Tikhonov, D. G., Zakharova, A. E. and Neustroeva, T. S. (2018). Does Yakut folklore contain information on Neanderthals and Denisovans? Istoricheskaya etnologiya – Historical Ethnology 3(1): 14-28.
Tucci, Serena et al. (2018). Evolutionary history and adaptation of a human pygmy population of Flores Island, Indonesia. Science 361(6401): 511-516. [Abstract]
Vernot, B., S. Tucci, J. Kelso, J.G. Schraiber, A.B. Wolf, R.M. Gittelman, M. Dannemann, S. Grote, R.C. McCoy, H. Norton, L.B. Scheinfeldt, D.A. Merriwether, G. Koki, J.S. Friedlaender, J. Wakefield, S. Pääbo and J.M. Akey. 2016. Excavating Neandertal and Denisovan DNA from the genomes of Melanesian individuals. Science DOI: 10.1126/science.aad9416
Vicedomini, R., Polit, L., Condemi, S., Longo, L. and Carbone, A. (2021). Dietary adaptation in Neandertal, Denisovan and Sapiens revealed by gene copy number variation. bioRxiv preprint. https://doi.org/10.1101/2021.10.30.466563
Vogel, Gretchen. (2018). Ancient DNA reveals tryst between extinct human species. Science 361(6404): 737. [Abstract]
Waddell, P. J., J. Ramos, and X. Tan. (2011). Homo denisova, Correspondence Spectral Analysis, Finite Sites Reticulate Hierarchical Coalescent Models and the Ron Jeremy Hypothesis. arXiv (Quantitative Biology) 1112.6424, pp 1-43.
Williams, Sloan R. (2019). The Neanderthal and Denisovan Genomes, pp. 69-88. In: O'Rourke, Dennis H. (ed.). A Companion to Anthropological Genetics. John Wiley & Sons. [Summary]
Zavala, Elena I. et al. (2021). Pleistocene sediment DNA reveals hominin and faunal turnovers at Denisova Cave. Nature. https://doi.org/10.1038/s41586-021-03675-0
http://www.heritagedaily.com/2013/10/mysterious-ancient-human-crossed-wallaces-line/99233
http://www.newscientist.com/article/dn24603-mystery-human-species-emerges-from-denisovan-genome.html#.UoyYINLXAdQ
http://frenchtribune.com/teneur/1320775-extinct-hominin-species-genome-contains-unusual-snippets-dna
http://www.newscientist.com/article/dn24603-mystery-human-species-emerges-from-denisovan-genome.html
https://twilightbeasts.wordpress.com/2015/04/29/who-were-the-denisovans-anyway/
https://www.the-scientist.com/?articles.view/articleNo/52078/title/Homo-Sapiens-Interbred-With-Denisovans-From-Two-Different-Populations/
https://arstechnica.com/science/2018/03/modern-humans-interbred-with-denisovans-more-than-once/
http://extinctanimals.proboards.com/thread/21586/homo-sp-nov-denisovans
https://www.dailymail.co.uk/sciencetech/article-6768561/First-piece-Denisovan-skull-discovered.html
https://www.sciencemag.org/news/2019/09/ancient-dna-puts-face-mysterious-denisovans-extinct-cousins-neanderthals